Trifluoroacetic acid (TFA) is a versatile and widely used organic solvent with various applications in peptide synthesis and analysis. It is a naturally occurring, biodegradable, and strong acid with a pKa of 0.23, making it an ideal catalyst for various organic transformations.
General Description
TFA is a colorless, volatile, and fuming liquid with a pungent odor. It is miscible with water and various organic solvents, including fluorinated hydrocarbons, methanol, ethanol, ethyl ether, acetone, benzene, carbon tetrachloride, and hexane. Its specific gravity is 1.5351 g/cm³ at 1°C, and it has a melting point of -15.2°C and a boiling point of 72.4°C.
Chemical Info
No chemical information available.
